Dissertations

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Summer 2023

NameThesis TitleAdvisor
Lin, ShujunDevelopment of in vivo Human Brain DTI-MREKlatt, Dieter
Liu, SongyunChemical Alterations of Periprosthetic Tissue and Joint Replacements: A Vibrational Spectroscopy StudyPourzal, Robin
Salehabadi, MelikaDecoupling Uniaxial Prestress and Waveguide Effects from Dynamic ElastographyRoyston, Thomas
Wang, BoshenPredicting Pathological Effect of Mutation and Identifying Cancer Driver Event Based on Protein StructureLiang, Jie

Spring 2023

NameThesis TitleAdvisor
Brown, GraceMicropatterned Co-cultures of the Liver and the Heart for Drug Screening and Cell TherapyKhetani, Salman
Choi, HyunjunThe Development of Alginate-Based Microspheres for Endovascular ApplicationsKim, Dong-Hyun
Kefi, AmiraImproving the Human Genome Annotation Using Integrative Analysis and Deep Learning Methods.Liu, Chunyu
Le, DavidQuantitative Image Analysis for Objective Classification of Retinal DiseasesYao, Xincheng
Manuchehrfar, FaridProbability Landscape and Its Rotational Flux in Complex Systems: Construction and Topological StructureLiang, Jie
Phakatkar, AbhijitTEM Studies of Multielement Nanomaterials and Bacteria Interactions in the Aqueous EnvironmentsShokuhfar, Tolou; Shahbazian-Yassar, Reza
Sun, MichaelEvaluation of Corneal Biomechanics Using Silk Biomaterials and Optical Coherence ElastographyRosenblatt, Mark
Wang, WangfeiRole of Post-transcriptional Dysregulation and Aberrant Microbiota in Obstructive Lung DiseasePerkins, David; Finn, Patricia

Fall 2022

NameThesis TitleAdvisor
Gao, ShangMachine Learning Approaches for the Integrative Analysis of Multi-omics DataDai, Yang; Rehman, Jalees
Liu, JenniferDesign of Engineered Substrates to Modulate Human Liver Cell Phenotype for Disease ModelingKhetani, Salman
Saha, SoumyaThe Role of Ethanol in Inherently Selective Atomic Layer Deposition and in Making Bioactive CoatingTakoudis, Christos
Wu, ShanshanEnergy Flow Perspective on the Mechanism of Conformational Dynamics in BiomoleculesMa, Ao

Summer 2022

NameThesis TitleAdvisor
Bandela, MounicaRole of Cortactin in Cigarette Smoke-Induced Lung Endothelial DysfunctionDudek, Steven
Gao, HuaViscoelastic and Inertial Focusing of Asymmetric Cells in Spiral ChannelsPapautsky, Ian
Geng, XueNeuroprotective Effects of Docosahexaenoic Acid on Neuronal Cell FunctionLee, James
Monckton, ChaseEngineering High Content and Multicellular Human Liver Platforms for Drug DevelopmentKhetani, Salman
Tangen, KevinVirtual CNS Test Station for Computational Prediction of Species Transport in the CSFLinninger, Andreas
Zhang, ZhehaoMultiplexed Electrochemical Sensors Based on Printed Circuit BoardPapautsky, Ian

Spring 2022

XThesis TitleAdvisor
Kim, TaehoonFunctional Optical Tomography of the Retina in Mouse Models with Neurodegenerative DiseasesYao, Xincheng
Lam, TrinhMicrofluidic Device for Studies of Bacterial Genetic Transformation in Streptococcus pneumoniaeEddington, David

Fall 2021

NameThesis TitleAdvisor
Chang, ClaireThe Role of G alpha 13 in Integrin-dependent Neutrophil MigrationDu, Xiaoping
Khan, MohammedBiomimetic Surfaces for the Study of Outside-In Signaling in NeutrophilsMalik, Asrar
Mukherjee, PrithvirajFractionation and Focusing of Leukocytes using Inertial MicrofluidicsPapautsky, Ian
Reiman, DerekDeep Learning Frameworks for Multi-omics Analyses of the Microbiome in Disease StudiesDai, Yang
Sheth, NiharDevelopment of an Autonomous Platform for Surgical Simulation and TrainingLuciano, Cristian
Teng, TaoMembrane-Cytoskeleton Connectivity in Alzheimer’s Disease: From Aβ Clearance to TauSpreading by MicrogliaLee, James
NameTitleAdvisor
Adiraj Iyer, MaheshwarControl of Cell Culture Microenvironment Using Programmable SystemsEddington, David
Fortel, IgorExcitation-Inhibition Balance: A Study of Brain Network Dynamics Using Statistical MechanicsLeow, Alex and Schonfeld, Dan
Marjanovic, NicholasAugmented Reality Haptic Trainer for Urinary CatheterizationNiederberger, Craig
Pandya, ShrikantSperm Hunter - Neural Network Model for Sperm Identification in Azoospermic MalesNiederberger, Craig
Yazdanpanah, GhasemFabricating Natural Tunable Bioactive Biomaterials for Corneal Repair and RegenerationDjalilian, Ali
NameTitleAdvisor
Kukla, DavidMultiscale Human Liver Platforms for Disease Modeling, Drug Development, and Regenerative MedicineKhetani, Salman
Kunzer, BrianDevelopment and Application of Computational Tools for Multi-Electrode ElectroretinographyHetling, John
Lenzini, StephenThe Biophysical Characteristics of Extracellular Vesicle Production and TransportShin, Jae-Won
Maharathi, BiswajitSpatial-Temporal Network of Epileptic Spikes in Human NeocortexPatton, James; Loeb, Jeffrey
Perez-Rathke, AlanMechanisms of Biological Functions Through Polymer Deep Sampling: Protein Gating and Chromatin FoldingLiang, Jie
Scotti, AlessandroA Novel Z-Spectrum MRI For The Detection Of Brown And Browning Adipose TissueCai, Kejia
Zhong, ZhengAdvancing Spatial and Temporal Resolution of MRI for Biological and Physical ApplicationsZhou, Xiaohong Joe
NameTitleAdvisor
Mehta, RahulLearning Patterns of Somatic Mutations and Medical Images in Human Cancer With Machine LearningKaraman, Muge
Parmar, PriteshOptimal Process Modeling for Assessment and Enhancement of Error-Based Motor LearningPatton, James
NameTitleAdvisor
Alam, MinhajQuantitative Analysis and Automated Classification of Retinal ImagesYao, Xincheng
Jambusaria, AnkitComputational Investigation of Endothelial Heterogeneity During Homeostasis and InflammationRehman, Jalees; Malik, Asrar
Majumdar, ShreyanDevelopment of Magnetic Resonance Elastography for Assessing Small Regions of Interest in Murine ModelsKlatt, Dieter
NameTitleAdvisor
Majeed, YazanComputational Modeling to Predict and Affect Recovery After StrokePatton, James
Banner, DavidvTEM of Biologically Induced Reactions: Kidney Stone Mineralization and E. coli-Fiber InteractionsShokuhfar, Tolou
Guidetti, MartinaUnderstanding Mechanical Wave Propagation in Anisotropic Samples through Magnetic Resonance ElastographyRoyston, Thomas
Hartung, GrantMulti-Scale Simulation of Cerebral Blood Flow and Oxygen Exchange for the Entire Mouse BrainLinninger, Andreas
Lu, YimingQuantitative Investigation of Stimulus-evoked Intrinsic Optical Signal Change in Retinal PhotoreceptorsYao, Xincheng
Narayanan, SuryaIn situ TEM to Study Iron Crystallization Mechanism in FerritinShokuhfar, Tolou
Shareef, FarahLight Attenuating Artificial Iris: Implantable and Contact Lens DesignsCho, Michael
Name Title Advisor
Ghosh, ShreyaQuantum Dot Based Aptasensors for the Detection of Biomolecules with Related Raman/SERS Spectral AnalysisStroscio, Michael
Meltem, UyanikTissue Structure Analysis Using Anomalous Diffusion Signal Decay Models in Magnetic Resonance ImagingMagin, Richard
Wright, ZacharyDistribution Analysis of Motor Actions for the Design of Customized Robot-Assisted TherapyPatton, James
Xu, JingtingComputational Analysis of DNA Methylation and Gene RegulationDai, Yang
NameTitleAdvisor
Anderson, NickolasDeposition and Characterization of Electronics Materials in Bionanotechnology and Micro/Nano-electronicsJursich, Gregory
Blank, KennethInfluence of Lumbar Fusion Alignment and Sitting Postures on the Biomechanics of Adjacent SegmentsPatwardhan, Avinash
Chen, ChangStructure-function Analysis of Inflammatory Bowel Disease Associated Proteins and Moonlighting ProteinsJeffery, Constance
De, AyushmitaEffect of Fusion Methods on Adjacent Segment Biomechanics in a Lumbar Spine with Preexisting Conditions Natarajan, Raghu
Seonbyeong, KimMathematical Modeling of Aquaporin 4 Intracellular Transport and Design of Complex Distillation ProcessLinninger, Andreas
Thomas, JoelQuantitative Evaluation of Electrical Stimulation Therapy for Eye DiseaseHetling, John
Terebus, AnnaComputing Landscape, Velocity and Flux of Probability Mass in Gene Regulatory NetworksLiang, Jie
Tian, WeiComputational Investigation of Structural and Thermodynamic Properties of Beta-Barrel Membrane ProteinsLiang, Jie
NameTitle Advisor
Ghodsi, SeyedGraphene Liquid-Cell TEM Investigation of Confined LiquidsShokuhfar, Tolou
Knowlton, ChristopherA Gait-Dependent Model of Wear from Retrieved Polyethylene Components of Total Knee ReplacementsWimmer, Markus
Naqib, AnkurEvaluating PCR Bias Through Experimental Investigations of Complex Primer-Template InteractionsGreen, Stefan
Xing, MengqiUsing Electroencephalography-Based Connectomics for Pattern Learning on Psychiatric DisordersLeow, Alex
NameTitleAdvisor
Christoforidis, TheodorosMicrofluidic Devices for Control of Gaseous EnvironmentsEddington, David
Jones, TanekaExtrusion Based Bioprinting: An In Vitro Model for Dental Pulp Tissue EngineeringAlapati, Satish
NameTitleAdvisor
Bishal, ArghyaFunctionalization of Biomaterials with Atomic Layer Deposition for Tunable Performance EnhancementsTakoudis, Christos
Ghaffari, MahsaLarge-Scale Hemodynamic Analysis of Cerebral Arterial Tree with Parametric Mesh Generation TechniqueLinninger, Andreas
Gould, IanComputational Mathematics Elucidates the Dependence of Brain Perfusion on MicrocirculationLinninger, Andreas
Metwally, AhmedComputational Methods for Longitudinal Microbiome Analysis: Identification, Modeling, and ClassificationPerkins, David/Dai, Yang
Mkrtschjan, MichaelMechanical Inputs to Cardiac Fibroblasts and Myocytes Affect Structure, Function, and Signaling ResponseRussell, Brenda
Paredes, AndreEffects of Variable Energy Delivery on Leukocyte Kinetics and Wound HealingBartholomew, Amelia
Suryadevara, VidyaniRole of Phospholipase D in Idiopathic Pulmonary Fibrosis and FTIR Imaging to Detect FibrogenesisNatarajan, Viswanathan/Royston
NameTitleAdvisor
Bergau, DennisMachine Learning Prediction of Pre-Clinical Drug Induced QT Prolongation Liability and Pathway AnalysisLu, Hui
Henry, BrianThe Audible Human Project: Geometric and Acoustic Modeling in The Airways, Lungs and TorsoRoyston, Thomas
Patangay, ShrestaPattern Electroretinograpy in Peripheral Retina: System Development and Validation in Human SubjectsHetling, John
Qin, WenyiNovel Statistical Methods Through Data Integration for Disease-related Gene and Pathway DetectionLu, Hui
NameTitleAdvisor
Michael, GeorgeTribocorrosion Studies of Dental Materials, and the Clinical ImplicationsMagin, Richard
Khansari, MaziyarQuantitative Analysis of Ocular Microcirculation Images in Human Health and DiseaseShahidi, Mahnaz
Parikh, ParasMRI-based Curvature Assessment and High-Resolution T1 Mapping to Detect Cardiac Structural AbnormalitiesNg, Jason; Royston, Thomas
Rexius, MeganEngineered Systems for Controlled Hypoxia and ThermogenesisEddington, David
Wang, BenquanFunctional Optical Coherent Tomography of Stimulus-Evoked Intrinsic Optical Signals in the RetinaYao, Xincheng
Xing, YuanMicrofluidic Platform for In Vitro Study on the Development of Cell TherapyOberholzer, Jose
Larsen, PeterModeling Host-Microbiome InteractionsDai, Yang
Liu, CongInvestigation of Feature Selection Methods in High-Throughput Omics Data AnalysisLu, Hui
NameTitleAdvisor
Ahn, SangRole of Endothelial Potassium Channels in Vasodilation Under Normal and Dyslipidemic ConditionLevitan, Irena
Bogdanowicz, LeszekDiagnosis of Glaucoma by 3D Reconstruction of Optic Nerve Head with a Portable Ocular Imaging SystemHetling, John
Brennan, MartinDevices for Biological Systems: On-Chip Horizontal Gene Transfer and 3D-Printed Microfluidic ApplicationsEddington, David
Felder, AnthonyMulti-modal Imaging of Retinal OxygenationShahidi, Mahnaz
Jaishankar, DineshEngineering a Higher Efficacy Anti-Heparan Sulfate Peptide for an Entry-Based Antiviral TherapyShukla, Deepak
LeMaster, ElizabethSynergistic Effect of Hemodynamic Environment and Dyslipidemia on Endothelial BiomechanicsLevitan, Irena
Selner, AshleyThree-Dimensional Finite Element Models of Corneal Electroretinogram Potentials in RatHetling, John
Shah, AmitReshaping Movements Through Avoidance of Negative Events: A General Adaptive ControllerPatton, James
Srinivasan, GirishDevelopment of a Novel Data Acquisition Technique and a Software Tool for Quantitative Diffusion ImagingZhou, X. Joe
Varma, VishalQCL and FT-IR Spectroscopic Imaging to Identify Biomarkers for Transplant Outcome and CancerWalsh, Michael
Wang, ZhinanStudy of Hypoxia on Embryogenesis, Pharmaceutical Testing and Stem Cell Regulation Using Drosophila ModelCheng, Jun
NameTitleAdvisor
Hsu, ChihyangMedical Imaging Techniques for Characterizing Cerebral AngioarchitectureLinninger, Andreas
Mashiatulla, MaleehaStructural and Compositional Assessment of Bone and Articular Cartilage with Micro-Computed TomographySumner, D. Rick
Mendoza-Elias, JoshuaMicrofluidic-based Strategies to Improve Islet and Encapsulated Islet Transplant for Type I DiabetesOberholzer, Jose
Venugopal, InduIntrathecal Magnetic Drug Targeting for Treatment of Central Nervous System DiseasesLinninger, Andreas
Ye, AllenMultiple-Scale Analysis on the Fractal Structure of the Brain using Diffusion Magnetic Resonance ImagingMagin, Richard
Lin, MeishanComputational and Experimental Investigations of Folding Principles and Design of Outer Membrane ProteinsLiang, Jie
NameTitleAdvisor
Derafshi, ZahraMulti-Electrode Electroretinography: Measuring Spatial Differences in Corneal PotentialsHetling, John
Hall, CierraA Luminance Noise Approach to Target Post-Receptor Visual Pathways; Application to Optic Nerve DiseaseMcAnany, J. Jason
Gursoy, GamzeThree-Dimensional Chromosome Organization in Eukaryotes: Novel Computational ApproachesLiang, Jie
Zhao, JielingDynamic Cell Model with Cellular Signaling Network and Mechanical Forces for Tissue Pattern FormationLiang, Jie
NameTitleAdvisor
Horowitz, JustinMovement Intent and Its ConstructionPatton, James L.
Gerardo Mauleon Ramos3D Oxygen Microfluidic Platform for In Vitro Hypoxic StudiesEddington, David
Tang, KeEfficient Biased Sampling Methods for Biomacromolecules: Protein Loops and RNA Thermodynamic PredictionLiang, Jie
Trella, KatieHaptic Simulation of Prostate Cancer Based on Magnetic Resonance ElastographyLuciano, Cristian J.
NameTitleAdvisor
Moria Fisher BittmannCustomized Robotic Training Approaches Using the Statistics of Reaching ErrorsEddington
Zelenakova, JuliaEffect of Binge Alcohol Exposure on Intervertebral Disc Structure and Mechanical Properties in Adult RatsMagin
NameTitleAdvisor
Bochenek, MatthewImmuno-Isolation Strategies for Islet Transplantation into Rodent and Non-Human Primate ModelsOberholzer, Jose
Gutierrez, DianaThe Study of Non-Viral Nanoscale Delivery Systems for Islet TransplantationOberholzer, Jose
Khayatzadeh, SaeedEffect of Sagittal Malalignment on Cervical Spine BiomechanicsPatwardhan, Avinash
Meshik, XeniaQuantum Dot- and Aptamer-Based Nanostructures for Biological ApplicationsStroscio, Michael
Nourmohammadzadeh, MohammadApplication of Microfluidics in the Field of Diabetes and IsletsOberholzer, Jose
NameTitelAdvisor
Bang, ChiThe Role of Spectrosome and Centrosome in Asymmetric Stem Cell DivisionCheng, Jun
Butt, ArmanFunctionalized Ti-V Surfaces for Improved Osseointegration and Tribocorrosion of Biomedical ImplantsTakoudis, Christos
Parthasarathy, RajniNeprilysin-dependent Reduction of Amyloid-beta in Eye TissuesPepperberg, David
Hu, HongIdentification of Transcriptional Regulatory Elements: Novel Machine Learning ApproachesDai, Yang
NameTitleAdvisor
Eik Lang LauDesigning and Evaluating Carbide-Derived Carbon As a Novel Biomaterial for Hip ImplantsCho/McNallan
Lueshen, EricDesign of Drug Delivery Methods for the Brain and Central Nervous SystemLinninger, Andreas
Sui, YiMulti-dimensional Excitation in MRI: New Development and ApplicationsZhou, X. Joe
NameTitleAdvisor
Huang, Chun-ChiehSynthesis And Characterization of Leucine Zipper Hydrogel For Tissue RegenerationGeorge, Anne
Faezeh Jahanmiri NezhadSurface EMG Examination of Amyotrophic Lateral SclerosisRymer, William Zev
Kurani, AjayResting State fMRI in Parkinson’s Disease and Progressive Supranuclear PalsyVaillancourt, David
Yenkie, KirtiStochastic Processes from Batch Crystallization to In-vitro FertilizationDiwekar, Urmila
NameTitleAdvisor
Broughton, KathleenBioengineering Approaches to Control Micromechanics for Analysis of Cardiomyocyte ContractilityRussell, Brenda
Schwartz, BenjaminDynamic Analysis of Multiply Connected Bodies for Magnetic Resonance ElastographyMagin
Teng, Pang-YuQuantification of Retinal Oxygen Extraction Fraction and Vascular Oxygen Tension GradientsShahidi, Mahnaz
Yin, ZiyingMR Relaxation, Diffusion, and Stiffness Characterization of Engineered Cartilage TissueMagin
NameTitleAdvisor
Doroudian, GolnarDelivery of Mechanical and Chemical Stimuli to Advance RegenerationRussell, Brenda
Kuo, Hsien-ChiDevelopment and Evaluation of Computerized Segmentation Algorithm for 3D Multimodality Breast ImagesGiger, Maryellen
Parthiban, SujeethA Novel Method to Determine the Impact of Different Saddle Designs on Male Cyclists' Perineal Blood FlowNiederberger, Craig
Genchev, GeorgiComputational Studies of Mechanical Signal Transduction in ProteinsLu
Xu, YunProtein Design and Chromatin Structure: Novel Computational ApproachesLiang
NameTitleAdvisor
Mulger, EmilyInvestigation of Speech for Communicative Brain-Computer InterfacePatton
Roqueiro, DamianComputational Methods to Study Gene Regulation Using Genomic, Epigenomic and Chromosome Conformation DataDai