11/22 – Ashutosh Agarwal, University of Miami
Biomedical Engineering Seminar
November 22, 2024
11:00 AM - 12:00 PM
Location
BME Seminar in SEO 236
Address
851 S Morgan St, Chicago, IL 60607
Calendar
Download iCal FileSpeaker:
Ashutosh Agarwal, Ph.D.
Associate Professor
University of Miami, Department of Biomedical Engineering
Title: Human Organoids on a Chip
Abstract: Organs on Chips are being designed as accurate models of healthy and diseased human organs. These collaborative ventures seek to replace the current paradigm of high quantity, low quality data with limited applicability to the human patient with mid-quantity, high quality data that will eventually be patient specific. However, multiple daunting, yet scientifically fertile roadblocks will need to be addressed along the way: identifying a robust source of primary or stem cell derived human tissues; recapitulation of organ-specific microenvironments and architectures; development of a universal culture media for multiple cell/tissue types; agile deployment of multiple chips through a network of pumps, valves, switches, collection ports, and sampling ports; integration of on-chip sensors and analytics for real-time evaluation of function; extrapolation of in-vitro results to in vivo outcomes; allometric scaling laws of organ chips with respect to each other; and finally, translating these devices in a scalable manner into the laboratories of basic scientists and pharmaceutical companies. This seminar will cover our contributions in each of these thrust areas.
Date posted
Nov 8, 2024
Date updated
Nov 8, 2024