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Sep 3 2021

9/3 – Zongmin Zhao, University of Illinois Chicago

Biomedical Engineering Seminar

September 3, 2021

12:00 PM - 1:00 PM


SEO 236


851 S. Morgan St, Chicago, IL 60607, Chicago, IL 60612

Watch this seminar live here>>

Seminar: Zongmin Zhao, PhD

Blood Cell-Inspired Strategies for Drug Delivery and Immunoengineering

Abstract: Delivering therapeutics to target sites while avoiding off-target accumulation is the key in designing therapies with desired efficacy and acceptable toxicity. To achieve this, a plethora of drug delivery systems including nanocarriers have been explored to improve the biological outcomes of respective drugs. However, majority of intravenously administered nanocarriers have so far failed to show desired accumulation in target sites, owing to key hurdles such as poor circulation and the inability to negotiate with significant biological barriers. Inspired by nature, intrinsic biology has provided several successful examples of “carriers” in the form of blood circulatory cells, which uniquely tackle hurdles faced by synthetic nanocarrier systems. Toward this end, we have explored blood cell-inspired Trojan Horse strategies (“cellular hitchhiking”) for directing therapeutics to their target sites. In this talk, I will discuss the principles of “cellular hitchhiking” for targeted drug delivery and discuss our recent efforts in leveraging this concept to address grand challenges in cancer therapy and immunoengineering.


UIC Biomedical Engineering

Date posted

Aug 11, 2021

Date updated

Aug 13, 2021