12/3 – Savas Tay, University of Chicago
Biomedical Engineering Seminar
December 3, 2021
12:00 PM - 1:00 PM
Location
SEO 236
Address
851 S. Morgan St, Chicago, IL 60607, Chicago, IL 60612
Calendar
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Speaker: Savas Tay, PhD
Professor, Pritzker School of Molecular Engineering, The Institute for Genomics and Systems Biology
University of Chicago
Title: Quantitative single cell analysis and modeling to understand and manipulate immune networks
Abstract:
Biological functions are controlled by the coordinated action of many genes and their products. Furthermore, biological systems are subject to variation and noise, necessitating measurements on individual cells. Understanding the systems-level behavior of highly interconnected gene networks is a prerequisite for successful applications in biology and medicine. In this talk, I will describe the use of microfluidic live cell analysis, single cell techniques, and mathematical modeling to develop a quantitative framework for understanding the emergent properties of complex signaling systems, and insights from these studies on how to use multi-point perturbations to such systems to achieve synthetic function in immune networks. I will also talk about the new technologies we have been developing in single cell proteomics and highly multiplexed microfluidic cellular analysis. Finally, I will discuss how this engineering approach can be used to address various diseases like sepsis and COVID-19.
Date posted
Nov 29, 2021
Date updated
Nov 29, 2021