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BioE PhD student’s research into noninvasive eye imaging techniques selected as feature article in latest Experimental Biology and Medicine journal


Recent research from the Richard and Loan Hill Department of Bioengineering has shown noninvasive imaging techniques can be used to study eye development in mouse models, which will help improve scientists understanding of normal and pathological eye development.

The paper based on the research, which was led by PhD student Taehoon Kim, was selected as the feature article for the July 2019 issue of Experimental Biology and Medicine. The article is titled “Functional OCT angiography reveals early physiological dysfunction of hyaloid vasculature in developing mouse eye” and was profiled by both Medical Xpress and PR Newswire.

Kim worked with his advisor Xincheng Yao, Richard and Loan Hill Professor of Bioengineering and Ophthalmology, to study the feasibility of using optical coherence tomography and angiography to image hyaloid vascular system regression in the developing mouse eye. They noted abnormalities in HVS regression can lead to eye disorders and vision loss.

“We anticipate that concurrent OCT and OCTA observation in normal and diseased animal models will be valuable in unraveling the complex mechanisms of the HVS regression and permit correlation with normal eye development and abnormal persistent hyaloid conditions,” Yao said.

Yao and UIC Postdoctoral Researcher Taeyoon Son also contributed to the paper.

You can learn more about Kim and Yao’s work by visiting the website for the Biomedical Optics and Functional Imaging Laboratory.