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BEGIN:VEVENT
UID:2026041403393020201123T12000020201123T13000069de5fb2dec2d@uic.edu
CATEGORIES:MEETING
STATUS:TENTATIVE
DTSTAMP:20201007T015608
DTSTART:20201123T120000
DTEND:20201123T130000
SUMMARY:11/23 -  Konstantinos Chronis, UIC
DESCRIPTION:Watch this webinar live with Zoom>>  Title: Reprogramming Cell fate    Abstract: The ability to reprogram cell lineage specification through the activity of master regulatory transcription factors (TFs) has the potential to transform disease modeling, drug screening, and cell therapy for regenerative medicine. Specifically, the derivation of induced Pluripotent Stem Cells (iPSCs) from somatic tissues ushered an era of personalized medicine through the development of therapeutics tailored to individual genetic background. Yet despite the increasing prominence of iPSCs in biology and disease, reprogramming strategies still require extensive time to complete and often yield heterogeneous mixtures of cells that are ill-suited for molecular analysis and cell therapy. Hence improving current reprogramming protocols and enabling conversion to highly specified and mature cell-types is of paramount importance if we are to implement reprogramming strategies as means for regenerative medicine. In this seminar, I will discuss how our lab addresses this major biomedical challenge, by employing a combination of multi-omic approaches, genome engineering, single cell tool development and computational technologies to delineate the actions of transcription factors in reprogramming somatic genetic networks towards a pluripotent state. | Event post: https://bme.uic.edu/events?page_id=5454
LOCATION:   Chicago IL 
CLASS:PRIVATE
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