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VERSION:2.0
PRODID:-//UIC
BEGIN:VEVENT
UID:2026051102561120251121T11000020251121T1200006a01454b598b8@uic.edu
CATEGORIES:MEETING
STATUS:TENTATIVE
DTSTAMP:20250919T092746
DTSTART:20251121T110000
DTEND:20251121T120000
SUMMARY:11/21 - Jing Hughes, Yale University School of Medicine
DESCRIPTION:Speaker:    Jing Hughes, MD, Ph.D.    Associate Professor of Medicine (Endocrinology)  Yale University School of Medicine        Title: Surprising features of primary cilia and their relationship to diabetes      Abstract: Primary cilia have long been regarded as static organelles, passively receiving extracellular cues for signal transduction to the cell. Our recent work demonstrates active motility in pancreatic islet primary cilia, which contributes to beta cell insulin secretion. Cilia possess localized glycolytic machinery capable of local ATP generation, which we propose fuels dynein-mediated motility. These data challenge the long-held view of cilia as static structures and provides evidence for metabolic-mechanical coupling in ciliary function, with implications for metabolic disease and ciliopathies. | Event post: https://bme.uic.edu/events?page_id=10375
LOCATION:BME Seminar in SEO 236 851 S Morgan St  Chicago IL 60607
CLASS:PRIVATE
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