4/20 – BME-CBQB Joint Seminar: Qin Ma, The Ohio State University
BME-CBQB Seminar (In-person event)
April 20, 2026
11:00 AM - 12:00 PM
Location
CDRLC 1422 (Multi-Purpose Room)
Address
850 W Taylor St, Chicago, IL 60607
Calendar
Download iCal FileThis is an in-person event in room CDRLC 1422 (Multi-Purpose Room), on east campus (directions).
Speaker:
Qin Ma, Ph.D.
Professor & Vice Chair for Research
Division Chief, Bioinformatics & Computational Biology
Department of Biomedical Informatics, College of Medicine | OSU
Director, Center for AI & Bioinformatics in Immuno-Oncology
Pelotonia Institute for Immuno-Oncology | OSUCCC
Director, Computational Health and Life Sciences
Translational Data Analytics Institute | OSU
Fellow, American Institute for Medical and Biological Engineering
Editor-in-Chief, Computational Biology and Chemistry
Title: Ad-hoc, post-hoc, and intrinsic-hoc in bioinformatics
Abstract: Disease mechanisms are usually context-dependent, multi-program states observed across tissues, perturbations, and modalities (e.g., single-cell and spatial transcriptomics, epigenomics, proteomics, and imaging), which makes computational analysis both powerful and fragile: methods can look strong in one cohort or platform yet fail when assumptions, tuning, or reference “gold standards” shift. Anchored in the mindset of Ad hoc, post hoc, and intrinsic-hoc in bioinformatics (Nature Biotechnology, 2025; s41587-025-02852-0), this talk frames bioinformatics analytics around three complementary design strategies and their trade-offs: ad hoc solutions that are practical and task-specific, post hoc strategies that emphasize systematic robustness and improve reproducibility, and intrinsic-hoc approaches that bake biological structure and interpretability into model design (e.g., pathway/network representations and mechanism-aware priors). Dr. Ma will illustrate how to select and hybridize these strategies for multi-modal data analysis and applications in biomedical research.
Date posted
Feb 19, 2026
Date updated
Feb 23, 2026