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Mar 18 2022

3/18 – Marcella Vaicik, IIT

March 18, 2022

12:00 PM - 1:00 PM


SEO 236 (in person event)


851 S. Morgan St, Chicago, IL 60607

This is an in person event in room SEO 236, you can also watch live here >>

Speaker: Marcella Vaicik, Ph.D. , Assistant Professor, Department of Biomedical Engineering, Illinois Institute of Technology

Title:Tissue Engineering and Drug Delivery Approaches for Regulation of Extracellulular Matrix in Adipose Tissue

Abstract: Cells interact with a network of proteins in the microenvironment known as the extracellular matrix (ECM). The functional importance of the ECM goes beyond structural support within the tissue. Components of the ECM interact with cells transmitting signals that regulate adhesion, migration, proliferation, apoptosis, or differentiation. In this presentation, the focus will be on the extracellular matrix in adipose tissue and on novel therapy development. Significant challenges in studying human disease are related to the current use of animal models. While important understanding can often be derived from animal models such as transgenic mice the ability to translate these findings in an animal model to clinically relevant understandings and ultimately treatment in humans is a significant limitation. This lecture will present findings from a transgenic knockout mouse model for laminin alpha 4, a key component of adipose ECM. Engineering strategies such as biocompatible nanocomposite emulsion for drug deliver to move from the mouse model towards therapeutic development will be discussed.


UIC Biomedical Engineering

Date posted

Mar 14, 2022

Date updated

Mar 14, 2022